Combined medication. Paracetamol has analgesic and antipyretic activity. Dianabol for salehistamine receptors I generation, eliminating the effects of histamine mediated through this receptor type. The action on the central nervous system caused by the blockade of H 3 histamine receptors in the brain, and inhibition of central cholinergic structures. It has a pronounced antihistamine activity, reduces or prevents histamine-induced smooth muscle spasms, increased capillary permeability, tissue edema, itching and flushing.
INDICATIONS Pain of mild to moderate severity (headache, toothache, pain when coughing and sinusitis, arthralgia, myalgia.) Disalgomenoreya; pain accompanied by sleeplessness.
CONTRAINDICATIONS Hypersensitivity, children under 12 years, pregnancy, breastfeeding.
DOSAGE AND ADMINISTRATION Inside, 1 to 2 tablets dianabol steroid every 6 hours until the disappearance of pain (no more than 8 tablets per day). For insomnia due to pain – 2 tablets before going to bed. Duration dianabol for sale of reception without consulting a doctor – not more than 10 days.
SIDE EFFECTS : Allergic reactions (skin rash, pruritus, urticaria, angioedema), nausea, epigastric pain; anemia, thrombocytopenia, agranulocytosis. Drowsiness, dry mouth, numbness of the oral mucosa, dizziness, tremor, nausea, headache, fatigue, decreased psychomotor speed reactions, photosensitivity, accommodation paresis, incoordination. Children may develop paradoxical insomnia, irritability and euphoria. With prolonged use at high doses – gepatotokeicheskoe effects, hemolytic anemia, aplastic anemia, methemoglobinemia, pancytopenia; nephrotoxicity (renal colic, Glycosuria, interstitial nephritis, papillary necrosis).
Overdose symptoms (caused by diphenhydramine): central nervous system depression, excitation of development (especially in children), or depression, dilated pupils, dry mouth, paresis of the gastrointestinal tract. Symptoms related to paracetamol: pale skin, loss of appetite, nausea, vomiting; gepatonekroz (necrosis due to the severity of intoxication is directly dependent on the degree of overdose). The increased activity of “liver” transaminases, increased prothrombin time (after 12-48 hours after admission); detailed clinical picture of liver damage manifests itself in 1-6 days. Rarely liver failure develops lightning dianabol review speed and can be complicated by renal insufficiency (tubular necrosis). Treatment: gastric lavage, if necessary – symptomatic therapy, including oxygen therapy, plasma substituting agents, donators of SH-groups and precursors of glutathione synthesis, methionine – in 8-9 hours after the overdose and N-acetylcysteine – 12 h Do not use epinephrine..
INTERACTION WITH OTHER DRUGS increases the effects of ethanol and drugs which depress the central nervous system. Monoamine oxidase inhibitors enhance the anticholinergic activity of diphenhydramine. Reduces the effectiveness of apomorphine prescribed as an emetic drug for the treatment of poisoning. The antagonistic interaction is marked with a joint appointment with psychostimulants. Increases anticholinergic effects of the drug with the m-anticholinergic activity. It enhances the action of monoamine oxidase inhibitors. Reduces the effectiveness of uricosuric drugs. Under the influence of paracetamol during removal of chloramphenicol increases 5 times. Chronic administration of acetaminophen may increase the effects of indirect anticoagulants. Simultaneous treatment with paracetamol and ethanol increases the risk of hepatotoxic effects and acute pancreatitis. Barbiturates, phenytoin, ethanol, rifampicin, phenylbutazone, tricyclic antidepressants and other stimulants microsomal oxidation dbol dosage increase the production of hydroxylated active metabolites, causing the possibility of severe intoxication with dianabol for sale small overdoses. Inhibitors of microsomal oxidation (cimetidine) reduce the risk of hepatotoxicity. Metoclopramide and domperidone to increase, and cholestyramine reduces the absorption. Myelotoxic drugs increase the expression gematotoksichnosti drug.
Cautions Avoid UV radiation. In the period of treatment should refrain from the use of ethanol (development of hepatotoxicity), motor vehicles and other driving activities potentially hazardous activities that require high concentration and psychomotor speed reactions. online anabolic steroids pharmacy
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